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Knowledge of ozone
 
Ozone in food, pharmaceutical, cosmetics, GMP certification, such as the application of space sterilization
First, the functional characteristics:
1, disinfection and sterilization
Ozone on bacteria, fungi, bacteria and other microorganisms has strong killing, killing virus is through direct damage to the material of RNA and DNA, and kill bacteria, virus microbial process is ozone first role in cell membrane and then destroying the membrane organization until dissolved death.
2, in addition to different odor
The ozone removal of mold, excellent fishy odor, odor effect, it can quickly oxidize and decompose the odor of chemical substances.
3, storage
Ozone diffuse gas disinfection, no dead ends, the machine can be realized automatically and bactericidal. For fruits and vegetables can not only sterilization mildew, to extend the shelf life, and rapid decomposition of fruit and vegetable respiration to exclude the rapid maturation and ethylene gas.
Two, object surface disinfection
In the manufacturing process of the drug often for raw materials, tools, packaging materials for surface disinfection, often use the disinfection cabinet, the transfer window, the traditional method is using ultraviolet disinfection, the problem is not thorough disinfection, so if used in such as the transfer window does not require high field is possible, but not as much as ozone effect is good. "Disinfection technical specifications" in detail, for immersion in the ozone gas in the surface of the object, contact for some time, the surface of the bacteria can be killed.
1. Application of ozone in pharmaceutical industry
Clean room in pharmaceutical industry and other industrial clean room are different, especially aseptic production preparation and pharmaceutical raw materials production, not only to control air is usually suspended state of aerosol particles, but also control or the number of microorganisms, both to provide a "sterile drug production to the corresponding air cleanliness of the environment (asepsis room).
Thoroughly efficient: produces a certain amount of ozone, in a relatively closed environment, evenly spread, inclusive, overcomes the shortcomings inherent in many corners of the existing in the ultraviolet sterilization, achieve all-round, rapid and efficient sterilization to.
Easy operation: according to the disinfection and sterilization requirements and the spatial volume, determine the type of ozone generator and ozone generating capacity and through the validation check bacteria number determine sterilizing time. When sterilization, the ozone output port is directly placed in a sterile room or HVAC system, and the controller can be used for 24 hours.
Gao Jie net: the use of ozone for disinfection and sterilization agent, 30 minutes after the shutdown, the remaining ozone can be gradually reduced to oxygen, while also can improve the quality of air, optimize the working environment. So ozone has been hailed as a "green disinfectant".
No adverse effects on the machines and equipment: ozone on air planktonic bacteria killing the ozone concentration is very low, generally, only need to 2~4PPM, the surface settlement colony (instead of the traditional chemical fumigation in disinfection) only need 10 ~ 15ppm around. The ozone concentration in the air is only 10-15 parts per million, which is 500 of the concentration of chemical fumigation. Due to the short sterilization process, the proper use of the conditions of the object is not enough to form the corrosion, which is particularly concerned about the.
Using the economy: the air as raw material, low energy consumption, low operating cost, good economic benefits.
Application of ozone in the pharmaceutical industry, 2:
Ozone in the application of pharmaceutical industry mainly includes the following aspects: GMP workshop and equipment, utensils surface sterilization; the second is the sterilization of central air conditioning system; the third is the locker room and work clothes disinfection, sterilization of the production and processing of water purification; five is the preparation of high concentration ozone disinfection solution.
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